Noncoding Genetic Variation and Gene Expression
نویسندگان
چکیده
منابع مشابه
Interpreting noncoding genetic variation in complex traits and human disease
Association studies provide genome-wide information about the genetic basis of complex disease, but medical research has focused primarily on protein-coding variants, owing to the difficulty of interpreting noncoding mutations. This picture has changed with advances in the systematic annotation of functional noncoding elements. Evolutionary conservation, functional genomics, chromatin state, se...
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ژورنال
عنوان ژورنال: Circulation: Genomic and Precision Medicine
سال: 2018
ISSN: 2574-8300,2574-8300
DOI: 10.1161/circgen.118.002109